Examinando Trabajos de Titulación - Medicina por Título
Mostrando 1 - 20 de 2117
Resultados por página
Opciones de ordenación
- ÍtemSolo MetadatosAbordaje diagnóstico y tratamiento del síndrome de Rendu-Osler-Weber(Universidad Católica de Cuenca., 2023) Ruiz Procel, Fabricio Josue; Puente Mosquera, Karola Adriana; 0705429892Rendu-Osler-Weber syndrome, also known as hereditary hemorrhagic telangiectasia, is a genetic disease of autosomal dominant hereditary predominance that is characterized by the presence of arteriovenous malformations and telangiectasia lesions especially in the skin, mucous membranes, digestive tract and respiratory system. The objective of this study is to describe the diagnostic and treatment approach. These malformations can cause recurrent episodes of bleeding leading to complications, such as anemia and heart failure. Its prevalence is approximately 1 in every 5,000 people worldwide. However, due to the underdiagnosed nature of the disease, it is possible that this number underestimates its true prevalence. It is crucial to determine the most effective and safe therapeutic options for the management of this syndrome. Including pharmacological measures, surgical interventions and interventional radiology therapies. The presence of arteriovenous malformations can cause strokes or hemorrhages, which demonstrates its relevance. Early and proper diagnosis is crucial and it is important to raise awareness in the medical community and educate health professionals, to facilitate their detection and diagnosis. Research into future therapies and genetic counseling would help identify biomarkers, specific treatment targets and innovative therapeutic approaches that can improve your health and quality of life.
- ÍtemSolo MetadatosAbordaje farmacológico (terapia de dolor) en pacientes oncológicos(Universidad Católica de Cuenca., 2022) Lalama Flores, Juan Daniel; Carrera Reyes, Rosa Eulalia; 0107131708
- ÍtemAcceso AbiertoAbordaje global y tratamiento local de quemaduras en adultos: revisión bibliográfica(Universidad Católica de Cuenca., 2022) Rivera Suco, Edwin Fabricio; Quinde Morocho, Ignacio Guillermo; 0104698857
- ÍtemSolo MetadatosAbordaje y tratamiento de la Diabetes Mellitus tipo 2 en población pediátrica(Universidad Católica de Cuenca., 2023) Vicuña Rojas, Erika Karyme; Alarcón Flores, María José; 1400787246Introduction: The review focused on the growing prevalence of Type 2 Diabetes Mellitus (T2DM) in children and adolescents, an emerging public health issue with associated severe complications. Methodology: We used the PRISMA methodology for the search, selection, and analysis of studies in academic and medical databases. The selected studies focused on T2DM in children and adolescents, and those focusing on adults or Type 1 diabetes were excluded. Results: An alarming increase in the prevalence of T2DM in the pediatric population was found. Risk factors are similar to those of adults, but disease management is different in children. The first-line therapy, metformin, appears to be less effective in children, highlighting the need for personalized and evidence-based treatment strategies. Conclusion: T2DM in children and adolescents requires immediate attention and effective prevention and treatment strategies. The importance of family support and education in managing this condition was underscored.
- ÍtemAcceso AbiertoAbsceso pancreático secundario a pancreatitis aguda: actualización(Universidad Católica de Cuenca., 2023) Arteaga Sarmiento, María Camila; Hugo Merino, Gabriel; 0104562632Background: Pancreatic and peripancreatic collections, with or without necrotic content, as well as abscesses, are known as local complications of severe acute pancreatitis, occurring within 20-40% of patients. It is usually associated with organ dysfunction and a high mortality rate. When the collection presents necrotic content and organ failure, and is over infected;, the mortality rate would be within 35.2%, meanwhile, mortality is at 19.8% in sterile necrosis plus organ failure. Worldwide, the incidence of acute pancreatitis ranges from 4.9 to 7.4 cases per 100,000 inhabitants. In Latin America, the incidence of this pathology is 15.9 cases per 100,000 inhabitants. Objective: To describe the clinical presentation, diagnostic methods, and current treatment of pancreatic abscess resulting from the complication of acute pancreatitis. Methodology: A bibliographic review was performed by searching scientific articles in databases such as Cochrane, Medline, PubMed, and Elsevier from 2017 onwards. Conclusion: Pancreatic abscess is considered a rare pathology with variable clinical presentation, but it can lead to multiorgan failure and patient death without timely treatment.
- ÍtemSolo MetadatosÁcido hialuronico vs plasma rico en plaquetas en el manejo inicial de la artrosis de rodilla(Universidad Católica de Cuenca., 2023) Calle Tandazo, Carlos Steeven; Flores Flores, Pedro Martin; 0706041498Background: knee osteoarthritis, a chronic degenerative disease, is a global health issue affecting populations in various regions of the world. This condition manifests through symptoms such as pain, stiffness, and a noticeable reduction in joint mobility. Hence, this study is focused on establishing the efficacy of Hyaluronic Acid vs. Platelet-Rich Plasma in the treatment of knee osteoarthritis. Objective: To determine the relative effectiveness of hyaluronic acid and platelet-rich plasma in the treatment of knee osteoarthritis, through a bibliographic review. Methodology: a comprehensive search for information was conducted in academic databases in both Spanish and English, such as PubMed, Scopus, Scielo, and Elsevier. Studies from the past 6 years were included to ensure the relevance of the selected studies. Results: the reviewed studies indicate that Platelet-Rich Plasma (PRP) outperforms Hyaluronic Acid (HA) in the treatment of knee osteoarthritis, offering greater pain relief and significantly improving patients' function and quality of life. This superiority is consistent across different measurements and over time.
- ÍtemAcceso AbiertoÁcido tranexámico: reducción de la mortalidad en pacientes víctimas de trauma severo y riesgo de hemorragia(Universidad Católica de Cuenca., 2023) Cordero Cobos, Maria Emilia; Bueno Castro, Andrés Santiago; 0106873169Massive hemorrhage and subsequent transfusions are associated with significant mortality and morbidity rates in trauma/post-surgical patients. Recent evidence has demonstrated that antifibrinolytic medications can effectively reduce blood loss in various clinical contexts. This review aims to help doctors explore their use through the available evidence on Tranexamic Acid (ATX) therapy, develop appropriate dosing regimens, and understand their expanding scope of applications. OBJECTIVE: To determine the Tranexamic Acid effectiveness in managing hemorrhage in trauma patients and its role in reducing mortality. METHODOLOGY: In this study, a literature review was conducted by compiling research from different databases, including PubMed, ScienceDirect, and Scopus. Keywords such as "TRANEXAMIC ACID," "HEMORRHAGE," "MORTALITY," "SURVIVAL RATE," "EFFICACY," and "DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS" will be used. In addition, the Boolean operators "AND," "NOT," and "OR" will be employed. RESULTS: Tranexamic Acid is an effective blood-sparing drug, seemingly without serious side effects in treating clinically significant hemorrhage. ATX usage will likely continue to increase, supported by various clinical guidelines and health organizations. In-depth quantitative studies are crucial to determine the optimal dose and efficacy of the drug, as these factors vary depending on the specific clinical setting in which it is used.
- ÍtemEmbargoÁcido úrico como factor predictor de apoyo diagnóstico y complicaciones materno – neonatales en preeclampsia(Universidad Católica de Cuenca., 2024) Mayancela Bermeo, Erika Jacqueline; Tapia Cárdenas, Jeanneth Patricia; 0106458318BACKGROUND: Preeclampsia is a progressive and irreversible systemic vascular disease with severe maternal and neonatal repercussions. World Health Organization (WHO) indicates that it is the leading cause of neonatal maternal morbidity and mortality. Every 3 minutes, a woman dies from this pathology worldwide, resulting in 76,000 maternal deaths and 500,000 neonatal deaths annually. OBJECTIVE: To collect updated information about uric acid as a predictor of diagnostic support and maternal-neonatal complications in preeclampsia. METHODOLOGY: A bibliographic review was conducted, including 14 articles that met the eligibility criteria. The information search used Scopus, Taylor & Francis, PubMed, Medline, Springer, and ScienceDirect databases. The information was consolidated in evidence tables. RESULTS: The uric acid cut-off for the diagnosis of preeclampsia ranges from 3.94 mg/dL to 5 mg/dL. Neonatal complications > 4.25 mg/dL give adverse outcomes, such as asphyxia, low birth weight, and neonatal death. In maternal complications with > 4.58 mg/dL, mothers are prone to developing HELLP syndrome, eclampsia, acute renal failure, and placental abruption. The effectiveness of uric acid as a diagnostic predictor was significant, with an area under the curve of 0.96. CONCLUSIONS: Uric acid may be helpful as a predictive factor for diagnostic support in preeclampsia. It is accessible due to its easy handling and low cost, determining the severity and appearance of adverse results and, in turn, alerting health personnel.