En este servicio en línea podrá consultar los trabajos académicos y de investigación
producidos en los diferentes campus de la Universidad Católica de Cuenca, en formato
digital: tesis, monografías, libros, artículos, etc.
Envíos recientes
Eficacia de la hidralazina versus nifedipino en el tratamiento de la preeclampsia: revisión sistemática
(Universidad Católica de Cuenca., 2025) Benalcázar Urgiles, Patricia Jacqueline; Naula Morocho, Johanna Veronica; Gallegos Vintimilla, Santiago Homero; 0107130221; 0106182850
Background: Among the most commonly used drugs in pregnant women diagnosed with preeclampsia are hydralazine and nifedipine. Their efficacy, as well as their onset of action, has been demonstrated to reach optimal levels. Their use is widespread, though not without concerns about adverse maternal and perinatal effects.
Objective: To characterize the efficacy of hydralazine versus nifedipine in treating preeclampsia.
Methodology: A systematic literature review was conducted involving searches in health databases, primarily PubMed, Elsevier, and SpringerLink, using predefined descriptors supported by Boolean operators such as AND and OR to optimize the searches. The PRISMA methodology was employed for screening and selection processes. All articles included were published after 2020 in English or Spanish as essential inclusion criteria. Sixty-four references met the established requirements, and 57 were included in the final bibliography.
Results: Twelve articles met the screening and suitability processes according to the designed objectives. The onset of action of both medications varied depending on the doses. Hydralazine demonstrated a slightly faster onset compared to nifedipine. Regarding efficacy levels, both drugs showed optimal results. However, nifedipine was associated with a higher incidence of adverse effects.
Conclusions: Hydralazine proved to be faster in its action. Both drugs achieved appropriate levels of efficacy, although nifedipine revealed a more significant number of adverse effects.
Keywords: antihypertensives, hydralazine, hypertension, nifedipine, preeclampsia
Proyecto de Titulación embargado con fines de publicación de impacto.
(Universidad Católica de Cuenca., 2025-01-16) Jimenez Rios , Andrea Rubi; Gualán Oviedo, Jimmy Rodrigo; 1450041932
Proyecto de Titulación embargado con fines de publicación de impacto.
(Universidad Católica de Cuenca, 2025) Lima Quizhpe , Cristina Elizabeth; Andrade Campoverde, Carlos
Proyecto de Titulación embargado con fines de publicación de impacto
(Universidad Católica de Cuenca., 2024) Barriga Ortis , Luis Gonzalo; Morquecho Salto , Julio Cesar; 1401237209
Factores asociados al abandono del esquema de vacunación en menores de 4 años de la parroquia de Sinincay durante el periodo enero–junio 2024
(Universidad Católica de Cuenca, 2025) Vásquez Cajamarca, Rosa María; Junior Pozo , Jose
Introduction: Despite all efforts to ensure the distribution and application of vaccines, there are people and groups who have concerns about the safety and need for the application of vaccines. Objective: To determine the factors associated with the abandonment of the vaccination schedule in children under 4 years of age in the parish of Sinincay. Methodology: A descriptive, quantitative, cross-sectional study was conducted. To determine the sample size, the probabilistic sampling technique was used, obtaining a total of 260 representatives or caregivers of children under 4 years of age as a sample. To collect the information, a previously designed survey was used, which addresses the health determining factors that influence the abandonment of the vaccination program. The data were processed in the SPSS statistical program, where descriptive statistics were performed and the chi-square statistical test was applied. Results: It was identified that 56.54% of the representatives reported complying with the vaccination schedules on time and 43.46% reported not complying on time. Regarding the determining factors for non-compliance with the vaccination schedule, 15.4% of the representatives reported lack of knowledge about the vaccine, 13.1% reported a shortage of the vaccine, and 40.4% reported a lack of guidance. Conclusion: The highest percentage of mothers reported that they did not comply with their children's vaccination schedule due to a lack of guidance. Likewise, the majority reported that they did not comply because they considered the vaccine to be harmful to the child or because of lack of knowledge about the vaccine.