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Item type: Ítem , Access status: Embargo , EMBARGADO POR MOTIVOS DE INVESTIGACIÓN(Universidad Católica de Cuenca., 2026) Escandón Carpio, Juan Francisco...Item type: Ítem , Access status: Acceso Abierto , Autismo y alteraciones en la composición y diversidad de la microbiota intestinal en población infanto-juvenil: Una revisión bibliográfica.(Universidad Católica de Cuenca., 2026) Gonzalez Tello, Doménica; Jaramillo Ordóñez, Dayana Stephania.Autism spectrum disorder (ASD) is associated with alterations in the composition and diversity of the gut microbiota, generating interest in understanding the role of the microbiota-gut-brain axis in the development and clinical presentation of the disorder. This study aimed to describe the relationship between autism and alterations in the gut microbiota in children and adolescents, define microbial changes, analyze the mechanisms through which these changes might influence neurological and emotional processes, and synthesize the available evidence. The study was conducted using a qualitative approach, with a narrative literature review design. The search was conducted in PubMed, ScienceDirect, Taylor & Francis, and PsycINFO using MeSH and DeCS descriptors related to gut microbiota, dysbiosis, autism spectrum disorder, children, and adolescents. Studies were included based on inclusion and exclusion criteria. A total of 31 studies were reviewed. The evidence showed a consistent association between ASD and gut microbiota alterations. A decrease in beneficial bacteria, such as Bifidobacterium, Prevotella, and Blautia, was identified, along with an increase in microorganisms such as Clostridium, Desulfovibrio, and Bacteroides. Furthermore, the studies suggested that gut dysbiosis may influence neurological and emotional processes through mechanisms related to inflammation, intestinal permeability, and the production of neurotransmitters and neuroactive metabolites. Although the studies could not establish a causal relationship, the findings led to the conclusion that there is a consistent association between alterations in the gut microbiota and ASD, highlighting the need for longitudinal studies using standardized methodologies to strengthen the evidence and support interdisciplinary intervention strategies.Item type: Ítem , Access status: Embargo , Proyecto de Titulación embargado para publicación. Estará disponible a la fecha de publicación o de cierre de embargo(Universidad Católica de Cuenca, 2026) Herrera Garzón, Evelyn MichelleItem type: Ítem , Access status: Acceso Abierto , Desarrollo y validación de niveles, narrativa y assets visuales para mejorar la coherencia ludo-narrativa en un videojuego 3D(Universidad Católica de Cuenca., 2026) Picón Cedillo, David SebastiánNarrative, level design, and concept art constitute fundamental pillars for shaping the story, spatial layout, and interaction in video games. This study addresses these components from the conceptualization and documentation perspective for the video game “Ashes of Faith,” with the goal of laying the foundations for an experience that strengthens ludo-narrative coherence and visual clarity in a 3D environment. To achieve this, a proposal was developed focused on story planning, character creation, dialogue design, and the construction of two interconnected zones, strictly limited to the scope of technical and conceptual design. The project is based on the Scrum agile methodology, organized into sprints and a Product Backlog divided into five phases: (i) analysis and planning, (ii) narrative design, (iii) visual and UI design, (iv) level design, and (v) integration and conceptual refinement. Additionally, tools such as Microsoft Word, Adobe Illustrator, and Kit Scenarist were also used. As a result, a comprehensive design document was produced, featuring a coherent narrative and a level design characterized by clear and easy-to-follow pathways. The theoretical effectiveness of the design was validated through user testing based on the Likert scale, which measured users’ perceptions of their understanding of the environment, the flow of the game, and their correct interpretation of the story.Item type: Ítem , Access status: Acceso Abierto , Estrés en la primera infancia y su correlaciòn con su funcionamiento familiar.(Universidad Católica de Cuenca., 2026) Quezada Illescas, Jonnathan DavidEarly childhood stress is not an isolated problem; rather, it results from a constant interaction between the dynamics of the child's social and family environment. This study analyzed early childhood stress and its correlation with family functioning, as well as the child’s own characteristics and skills. A narrative literature review was conducted, incorporating both qualitative and quantitative scientific data. The search was performed across databases including Scopus, PubMed, Dialnet, Google Scholar, Web of Science, Springer, Wiley Online Library, and ScienceDirect, using DeCS and MeSH terms, which facilitated a structured search for key terms related to childhood stress, family functioning, family relationships, child development, child mental health, family support, parental stress, and family dynamics, combined with Boolean operators (AND, OR, NOT) and a maximum publication age of seven years for all studies analyzed. Findings indicate that stressful experiences during early childhood significantly influence a child's psycho-emotional well-being and socio-emotional development. Key variables such as stability in family relationships, cohesion, parental relationship stability, and parenting styles directly affect the child's emotional adaptation. Early childhood stress is a complex, multidimensional phenomenon of social and health significance that is closely linked to the family environment, as it is not limited to isolated events but arises from the child's ongoing interaction with their personal, social, and family environment.
