Drogas psicodélicas como terapia alternativa a la depresión: una revisión sobre seguridad y efectividad

Abstract

Bibliographic evidence indicates that hallucinogenic substances, such as psilocybin and lysergic acid, can be a treatment for a variety of psychiatric disorders, including depression, as conventional treatments often show limited efficacy and may cause unwanted side effects. Although psychedelic drugs have long been considered dangerous substances lacking therapeutic value, recent research has changed that perception. The significance of this research on psychedelic drugs as an alternative therapy for depression lies in the fact that there are still many questions surrounding this topic, including the safety and effectiveness of these drugs with long-term therapeutic use. Objective: To delve into the future of administering psychedelic drugs in the treatment of depression safely and effectively. Methodology: A literature review of scientific data was conducted, considering primarily original articles in various specialized databases such as Scopus, PubMed, and Web of Science, employing terminology like "psychedelic drugs" and "depression." Results: Psychedelics have a positive effect with few or no adverse effects in the treatment of depression. It is proposed that updated knowledge regarding the use of these substances as a therapeutic alternative be compiled and further research promoted. Conclusions: Scientific evidence supports the therapeutic potential of psychedelics; it suggests reconsidering them as effective treatments for depression, expecting to offer new options to improve the lives of those suffering from this condition.