Terapia génica mediante el CRISPR/CASS en el síndrome de Hutchinson Gilford

Abstract

Hutchinson Gilford syndrome is defined as a disorder with an autosomal dominant inheritance pattern that is observed from the pediatric age, generating the appearance of accelerated premature aging due to a genetic mutation. The diagnosis is generally made in the first year of life due to the clinical manifestations that these patients present. Treatments to date are still under investigation, which seek to reversible the effects caused by this disease, in addition to being able to prevent it from manifesting. The present work consists of a bibliographical review, in which searches were carried out in the digital scientific bases.