Infuciciencia cardiaca aguda y furosemida a altas dosis

Abstract

Introduction: An imbalance in the contractile capacity of the heart causes acute heart failure. It is currently considered that there is no wholly established therapeutic management. So more than 80% of patients are treated with loop diuretics, mainly furosemide, which is the mainstay of treatment. Objective: To determine the benefit of high-dose furosemide in treating acute heart failure. Materials and methods: A literature review was performed based on the PRISMA guide of articles mentioning furosemide as a first-line drug in databases such as PubMed and Cochrane, that study acute heart failure and its therapeutic management. The studies reviewed are written in English and Spanish and published in the last five years. A total of 28 articles were analyzed. Results: According to articles, furosemide continues to be considered a therapeutic pillar. The evidence also mentions whether this drug is administered at high doses in continuous doses or boluses; it continues to be accepted. Conclusions: Considering the studies conducted, furosemide has not been shown to reduce mortality. However, it is still the therapeutic pillar of initial management, especially at high doses. Based on the research carried out in trials and comparative studies, there is currently no established management scheme. Keywords: acute heart failure, loop diuretics, high doses