Factores de riesgo de la resistencia a la insulina en adolescentes mujeres

Abstract

Introduction: Insulin resistance (IR) represents a global health problem because it is related to multiple diseases, making it difficult to establish a direct relationship. This problem is increasingly visible in adolescent females, which can have an adverse short- and long-term impact on this particular population group. Literature Review: IR in adolescent females is influenced by multiple factors, including excess body fat in visceral areas and a sedentary lifestyle. Other essential factors include diet, sleep quality, certain medications, and specific medical conditions such as polycystic ovary syndrome (PCOS). Abnormalities that increase the risk of IR include impaired fasting glucose, abnormalities in uric acid metabolism, high blood cholesterol and lipid levels, high blood pressure, clot formation, elevated inflammatory markers, endothelial dysfunction, history of stroke, history of type 2 diabetes (T2DM), racial differences, and lipid profiles. Conclusions: Understanding the risk factors for developing insulin resistance is crucial to designing effective preventive and therapeutic strategies, ranging from basic therapeutic approaches to surgical processes that mitigate the risk of IR and improve long-term health in this vulnerable population.