Infección por citomegalovirus en receptores de trasplante renal

Abstract

Cytomegalovirus (CMV) infection is a significant cause of morbidity and mortality in renal transplant recipients. This infection increases the risk of transplant rejection, the possibility of superinfection by opportunistic microorganisms, and other harmful indirect adverse consequences. The importance of this literature review is to deepen the understanding of cytomegalovirus infection in renal organ recipients, as it is a common but severe complication affecting these patients' well-being and quality of life. CMV infection will continue to be a problem for organ transplantation for decades to come. Much more effective antiviral therapies than ganciclovir are needed for prevention and/or treatment of the infection, as some strains have become resistant to ganciclovir. Further studies are needed to investigate the relationship between donor and recipient viral load, the risk of infection, and the serological pattern observed.