Avances terapéuticos en pacientes con sobrecrecimiento bacteriano intestinal

Abstract

Introduction: Intestinal bacterial overgrowth is a pathology that affects millions of people. About 15% of the general population suffers from bacterial overgrowth, associated with alterations in intestinal motility or previous surgical interventions, affecting about 50% of adults over 75. This pathology not only compromises quality of life due to its disturbing gastrointestinal manifestations, such as bloating and abdominal pain, but also implies considerable subdiagnosis attributed to the lack of accurate and effective underdiagnostic methods. General Objective: To describe the therapeutic advances in patients with intestinal bacterial overgrowth. Specific Objectives: • To compare different treatment approaches for intestinal bacterial overgrowth. • To generate recommendations for patients with intestinal bacterial overgrowth. Methodology: This review used PubMed, Scopus, and Web of Science databases. High-impact articles published in the last ten years detailing therapeutic advances in bacterial overgrowth were selected. The selection process included screening titles and abstracts and critically evaluating full texts based on predefined inclusion/exclusion criteria.

Conclusions: The findings indicate the need for more personalized treatments based on understanding the gut microbiome and its interactions with host physiology. The results underscore the importance of timely diagnosis. The therapeutic approaches reported in this review demonstrate superiority, reflected in the remarkable improvements in quality of life and reduced associated symptoms.