Síndrome poliglandular autoinmune tipo II: reporte de caso

Abstract

The autoimmune polyglandular syndrome type II, constitutes a clinical rarity and complex because it causes the failure of two or more endocrine glands and damage to non-endocrine organs, which makes it a serious condition, of which, until now, its cause is not completely known, however, its etiopathogenesis focuses on autoimmune and genetic factors, Its etiopathogenesis is centered on autoimmune and genetic factors, it is difficult to diagnose due to the lack of information and a standardized protocol, the clinical manifestations depend on the affected gland, it requires a complex treatment and its inadequate management can result in the death of the patient. This is the reason for the relevance of this case report. This is a 69-year-old female patient of Ecuadorian nationality, who has a history of gastritis, osteoporosis and osteoarthritis, who comes to the medical center for presenting hyperpigmentation of skin and mucous membranes, is referred to the endocrinology department where she is requested values of adrenocorticotropic hormone, the results showed an elevated adrenocorticotropic hormone, years later she was diagnosed with Hashimoto's thyroiditis, so an autoimmune polyglandular syndrome type II was suspected, due to the association of these two pathologies, the diagnosis was corroborated and the corresponding therapeutic follow-up was performed. The relevance of the case lies in its low incidence and in the diagnostic process, suspected in the context of a pathology unrelated to the underlying endocrine autoimmune pathology.