Trastornos hepatobiliares en los pacientes con enfermedad inflamatoria intestinal. Revisión bibliográfica

Abstract

Background: patients with inflammatory bowel disease (IBD) often experience hepatic complications, such as primary sclerosing cholangitis and nonalcoholic hepatic steatosis. Objective: to describe hepatobiliary disorders in patients with inflammatory bowel disease. Methodology: To carry out this bibliographic review, a narrative approach was carried out in which 15 scientific articles were selected from various databases such as Epistemonikos, Cochrane Library, Lilacs, TripDataBase, Medline, through identification – screening – eligibility – selection. Results: The diagnosis of hepatobiliary disorders in patients with IBD presents challenges due to the coexistence of IBD and pathologies such as primary sclerosing cholangitis, its impact on survival and quality of life, and the complexity of testing and follow-up. In addition, various therapeutic perspectives are explored. In addition, treatments based on the intestinal microbiota and the inhibition of miRNA-34a are analyzed. Conclusions: Interdisciplinary collaboration is essential, and continued research is vital to improve the diagnosis and management of these disorders. These advances offer hope of improving patients' quality of life and reducing complications.