Neoplasia intraepitelial cervical: nuevas tecnologías y avances en el diagnóstico

Abstract

Background: In the field of women's health, cervical intraepithelial neoplasia has received increasing attention due to its association with the development of cervical cancer. It is a significant public health concern as it is a major cause of morbidity and mortality in women. Objective: To determine new technologies and progress in the diagnosis of cervical intraepithelial neoplasia. Methodology: The following narrative literature review included original articles, systematic reviews, meta-analyses, and clinical trials published in the last five years without language restrictions.Various databases such as Scopus, Redalyc, and PubMed were used for gathering information. Finally, six articles were included to achieve the research objective. Results: For the diagnosis of cervical intraepithelial neoplasia, new tools such as Raman Spectroscopy are highlighted for their high sensitivity (94.46% and 91.32%) and specificity (97.72% and 92%). The miR-152 also shows promising results, with a sensitivity of 94.5% and a specificity of 96%. Bayesian Networks presented a sensitivity of 92.33% and a specificity of 95.7%. On the other hand, technologies like the epiCervix Test and High-Resolution Microendoscopy (HRME) show lower sensitivities and specificities, although still significant. Conclusions: These progresses represent a great potential to improve early detection and management of cervical intraepithelial neoplasia. However, it is crucial to continue with additional studies to confirm their efficacy and establish standardized protocols in clinical practice.