Enfermedad trofoblástica gestacional asociada a enfermedades tiroideas en mujeres en edad fértil

Abstract

Introduction: gestational trophoblastic disease is considered an unusual disease that produces complications in pregnancy. It is characterized by a group of malignant and benign pathologies that occur due to changes in the usual proliferation of the trophoblast. Less frequently, gestational trophoblastic disease is associated with thyroid diseases, only in 25 to 64% of cases, which can progress to thyrotoxicosis if they are not treated early and timely. As it is a pathology little studied in Ecuador, there is not enough information to explain in detail the conduct to be followed for the diagnosis and relevant and timely treatment. Objective: this study aimed to explain the association between gestational trophoblastic disease and thyroid diseases in women in the fertile period. Methodology: a literature review of scientific articles from the last five years was conducted by consulting databases such as Scopus, PubMed, Redalyc, SciELO, ScienceDirect, and Google Scholar. To do the research, articles were included without language restriction, and the DeCs keywords: molar pregnancy, thyroid diseases, trophoblastic disease, gestational, hydatidiform mole, and thyrotropin and MeSH ones: gestational trophoblastic disease, hydatidiform mole, molar pregnancy, thyroid diseases, and thyrotropin were used; the Boolean operators “And,” “Or,” and “Not” were also employed. Expected results: this literature review found the relationship between gestational trophoblastic disease and different thyroid diseases in women of childbearing age