Asociación entre la infección por Helicobacter pylori y el desarrollo de los linfomas MALT gástricos. Revisión sistemática

Abstract

Background: There is a risk of Helicobacter pylori infection ranging from 40% to 60% in highly developed countries. However, in developing countries, especially in Latin America, it can be as high as 90%, according to research published in Cuba. According to the Ministry of Public Health in Ecuador, the prevalence of Helicobacter pylori infections is 45% in rural areas and 47% in urban areas, with 23% of cases in asymptomatic patients. Primary gastric lymphomas account for more than 10% of lymphomas and more than 5% of gastric neoplasms. At the time of diagnosis, it presents as a low-grade tumor in 70-85% of cases. Objectives: To determine the relationship between Helicobacter pylori infection and the subsequent development of gastric mucosa-associated lymphoid tissue (MALT) lymphoma through a systematic review. Methods: This study conducted a systematic review of the descriptive and explanatory literature, using the PRISMA statement to carry out this procedure. Expected results: The results obtained from this study aimed to identify the relationship between the development of gastric MALT lymphomas in patients infected with Helicobacter pylori and the role of eradicating this bacterium in suppressing the lymphoma mentioned above. Keywords: infection, Helicobacter pylori, gastric MALT lymphoma, mucosa-associated lymphoid tissue, bacterium.