Tumor neuroendocrino y cáncer de próstata metacronico. Reporte de caso

Abstract

Introduction: This case report describes the coexistence of a neuroendocrine tumor and prostate cancer in a patient, diagnosed at different times (metachronous). Metachronous tumors, in which two types of cancer occur at different times, are rare, and the combination of a neuroendocrine tumor with prostate cancer is unusual. This study analyzes the clinical characteristics, diagnostic challenges, and therapeutic management of both types of cancer, providing valuable information for the treatment and follow-up of similar cases. This case report describes a 43-year-old male patient with a history of prostate cancer who visited a healthcare facility for a follow-up appointment, where a cluster of lymph nodes was identified in the left cervical region. Following diagnostic testing, the patient was diagnosed with: Large Cell Neuroendocrine Carcinoma of unknown primary origin with cervical, mediastinal, pulmonary, and retroperitoneal metastases. A prostatic origin was ruled out by immunohistochemistry. Conclusion: The diagnosis and treatment of these two types of metachronous primary cancers are complex and require a multidisciplinary approach to manage both prostate adenocarcinoma and the neuroendocrine carcinoma. This case highlights the importance of continuous surveillance to diagnose recurrence or a second primary tumor, thereby improving the patient's overall survival and quality of life