Papel del microbioma en el desarrollo de acné vulgaris

Abstract

Humans have millions of microorganisms in our bodies in symbiosis, 20 million microbial genes have been identified. Acne affects between 85%-90% of the world population who have western diets, this in turn affects psychologically, such as depression, anxiety, etc. The etiological bases of the disease are given by the family Cutibacterium Acnés (Propionibacterium) but the mechanism is not exactly explained. At present, there is evidence indicating that Staphylococcus Epidermidis of the skin and also the intestinal microbiome are involved. Therefore, in this study, the role of the intestinal and facial microbiome in the development of acne vulgaris has been sought, as well as the update of the mechanism based on the latest articles. As a conclusion and relevant findings, it was seen that the inflammation of acne is dependent on intestinal homeostasis, so the use of probiotics significantly reduces the inflammation of acne lesions, in addition, the results of the treatments can be seen after 2 weeks. Additionally, the use of antibiotics should be avoided because they reduce the healing process of the lesions