Métodos de diagnóstico y tratamiento para la confección entre dengue serotipo 1 y COVID-19

Abstract

Background: Dengue and COVID-19 are viral diseases and are quit life-threatening for infected individuals if left untreated; there are cases where patients can be affected by both diseases at the same time, so it is important to diagnose them and provide the most appropriate treatment because, in most cases, they could be fatal.

Objective: To determine the diagnoses and treatments for COVID-19 and Dengue co-infection.

Methodology: A narrative review of academic literature was conducted through scientific articles related to the symptoms, diagnosis, and treatment of the co-infection mentioned above, published in English or Spanish in the last five years. The search was performed on databases such as Scopus, SciELO, PubMed, and Medline; bibliographic descriptors DeCs/ MeSh were used as search strategies. Keywords in Spanish as Symptoms, COVID-19, Dengue, Diagnosis, and Treatment, along with Boolean operators "AND," "OR," and "NOT" were utilized. These articles were classified according to the criteria; 30 were chosen, and papers with insufficient information or duplicates were discarded.

Results: This co-infection is diagnosed by laboratory tests. Dengue and COVID-19 co-infection give an altered immune response. Treatment varies depending on the severity of the co-infection; if the signs and symptoms are mild, the treatment is symptomatic with antipyretics. In cases where the disease is exacerbated, the treatment includes prophylactic antimicrobials, mucolytics, and antimalarials. Fluids resuscitation, vasoactive substances, hemodialysis, and heparin are used in more severe cases, usually in older adults with comorbidities and critically ill patients.