Trombastenia de Glanzmann. Un reto diagnóstico

Abstract

The Glanzmann Thrombasthenia pathology is uncommon, with no concise data in Ecuador; it occurs in regions with high consanguinity. The diagnosis of this disease is complex due to differential prognosis and difficult access to specific tests; however, treatment can be simple and preventive in the case of other pathologies. This review aims to define and identify the diagnosis of Glanzmann Thrombasthenia. For this purpose, a literature review of scientific articles that met the following inclusion criteria was carried out: original articles, articles with quantitative methodologies, narrative literature reviews, articles in English and/or Spanish, human studies, systematic reviews, and meta-analyses, with 6 articles as a result. According to the compiled literature, diagnostics used for Glanzmann Thrombasthenia included peripheral smear morphology, flow cytometry, and light transmission aggregometry. Early and timely diagnosis is essential to initiate a treatment to improve the patient's quality of life.