Síndrome de superposición Asma-EPOC. Revisión Sistemática

Abstract

Background: Asthma-COPD (Chronic Obstructive Pulmonary Disease) Overlap Syndrome (ACOS) is the existence of both asthma and COPD pathologies in a single patient. Currently, this syndrome has been of special interest due to an increase in respiratory symptoms, a higher degree of exacerbations and a deteriorated lifestyle. General objective: To describe the update of the Asthma-COPD overlap syndrome. Specific objectives: To define COPD. To identify the new methods used for the diagnosis of COPD. To indicate the updated treatment for COPD. The research question is: What are the updates of the asthma-EPOC overlap syndrome? Methods: A search was made in PubMed, Scopus, and SciELO databases. We Open access, in full, or incomplete articles published in the last five years, in Portuguese, English, and Spanish were selected. The samples included young people, adults, older adults, and BALB/c rodents. Irrelevant or non-scientific articles were excluded. Conclusions: ACOS reveals the coexistence of asthma and COPD, associated with pollutants and a negative impact on lung function and quality of life. The importance of updated diagnostic methods and personalized treatments is highlighted. Keywords: asthma-COPD overlap syndrome, dyspnea, lung function, forced spirometry, mixed lung disorder