Antibioticoterapia en endocarditis infecciosa en pacientes con reemplazo valvular

Abstract

Introducion Disease of the endocardial surface of the heart is known as infective endocarditis (IE). This infection usually affects the heart valves (native or prosthetic) or a permanent heart device. The modified Duke criteria are used for the clinical diagnosis of IE; Furthermore, blood cultures continue to be the most important laboratory study to isolate the causative agents of infective endocarditis. For treatment, antimicrobial therapy in IE of prosthetic valves depends greatly on the diagnosis and the microorganism that is involved, therefore, endocarditis must be treated for pathogens and directed by blood cultures and antibiotic sensitivity. Objective Explain the effectiveness of antibiotic therapy in infective endocarditis in patients with valve replacement. Methodology databases such as Pubmed, Scopus, Web of Science and Cochrane were used, applying advanced search to compile 21 useful articles from the last 5 years with great relevance for this review. Expected results with this work we hope to explain the effectiveness of antibiotic therapy in infective endocarditis in patients with prosthetic valves, focusing on the most current antimicrobials to treat this disease.