Comparación: acetaminofén vs ibuprofeno para tratamiento de los síntomas en pacientes con infección por SARS-COV-2

Abstract

In 2019 in Wuhan, China, a new coronavirus called severe acute respiratory syndrome (SARS-CoV-2) causing the coronavirus disease (COVID 19) emerged. Its spread was rapid and after several reports the efficacy of some non-steroidal anti-inflammatory drugs, such as ibuprofen, was under suspicion. While paracetamol (acetaminophen) was suggested as a safe and recommendable alternative for early and home management of pain and fever in patients. Objective. To compare the use of acetaminophen vs ibuprofen for the treatment of symptoms in patients with SARS- COV-2 infection”. Methodology. The research is a bibliographic systematic review, where scientific articles published in journals related to health areas, available on search engines and digital platforms such as Scienedirect, Pubmed, Elsevier and Springer Link, were analyzed. The searches were carried out using previously defined keywords. Conclusions. the use of ibuprofen has been in doubt since its inception, in patients with COVID 19. However, no study claims to associate its use with significant increases in hospital stay, ICU admissions, need for mechanical ventilation, or mortality. However, acetaminophen has been used since the beginning, its use was not in question, but recent findings seem to indicate that it is not as effective as originally thought. Being quite inferior in the direct comparison with ibuprofen