Sensibilidad y especificidad de cervicometría versus fibronectina fetal en la predicción de parto prematuro: revisión sistemática

Abstract

Background: Preterm birth is one of the leading causes of neonatal morbidity and mortality, making the early identification of women at risk crucial. This systematic review analyzes and compares the sensitivity and specificity of two widely used diagnostic methods: cervical length measurement and fetal fibronectin test. Cervical length measurement, which evaluates cervical length via ultrasound, and fetal fibronectin detection, a protein indicative of extracellular matrix breakdown during pregnancy, have shown effectiveness in predicting preterm birth. However, their performance varies depending on factors such as test timing and population characteristics. Method: This study was conducted following the PRISMA framework by systematically reviewing scientific articles from databases such as Scopus, PubMed, and Cochrane Library, including articles that evaluated and compared these two methods regarding sensitivity and specificity. The information will be organized using the Rayyan platform, and the quality of the studies will be assessed using Joanna Briggs Institute forms. Expected Results: This study aims to determine which diagnostic method offers greater sensitivity and specificity in predicting preterm birth. Conclusions: This systematic review seeks to provide a better understanding of diagnostic methods for preventing preterm birth. Keywords: cervical length measurement, fetal fibronectin, preterm birth