El papel del macrófago en la migración de las células troncohematopoyéticas a la médula ósea

Abstract

The hematopoietic system, which encompasses the production of blood cells, is profoundly influenced by the presence and function of macrophages. These cells play a key role in regulating erythropoiesis, the immune response, and tissue repair. Their involvement ranges from the creation of specialized niches for red blood cell production to the modulation of the hematopoietic microenvironment and the inflammatory response. A thorough understanding of macrophage biology and function can significantly impact the diagnosis, treatment, and development of therapies for hematological disorders, such as leukemia and anemia. Their functional plasticity and diversity offer promising opportunities for more targeted and effective therapeutic interventions. However, further research is still needed to fully unravel the role of macrophages in hematological health and pathology, highlighting the importance of continuing research in this field in the search for new therapeutic strategies.