Actualización en Sepsis Neonatal Tardía. Revisión Sistemática

Abstract

Abstract: Late-onset sepsis in newborns represents an important event in the overall morbimortality in neonatal patients, especially in preterm and low and very low birth weight neonates. Late neonatal sepsis affects newborns after 72 hours of life and until the end of the neonatal period; the clinical manifestations are varied and nonspecific. The gold standard test for its diagnosis is the culture of blood, cerebrospinal fluid, or other focus of infection, and treatment is based on extended-spectrum antibiotic therapy. Objective: To conduct descriptive research by compiling current scientific articles of the last five years on late neonatal sepsis, advances, and innovations in its identification and clinical management. Methodology: Systematic review of non-experimental documentary design at descriptive level following PRISMA guidelines. Results: Thirty-four articles were reviewed; 25 matched the inclusion criteria; two papers were payable, so they could not be accessed; and seven articles were published over five years ago. Conclusions: Late neonatal sepsis is a severe infection that requires high clinical suspicion and appropriate management. Healthcare providers should pay close attention to the signs and symptoms of this disease and apply the necessary preventive policies to care for neonates' short- and long-term health and well-being.