El rol del intestino como diana con papel terapéutico en personas con enfermedades neurodegenerativas

Abstract

The influence of the intestinal microbiota on neurodegenerative diseases. Its correlation with diseases such as Parkinson's, Alzheimer's has given a remarkable impetus to new research. Just as Eamonn M. M. (2017) through his article "Microbiota-Brain-Gut Axis and Neurodegenerative Diseases" and the efficacy of the different studies carried out in animals, suggest that the gut-brain axis is intervened by the microbiome intestinal, thus forming the “microbiota-gut-brain axis””,Cryan et al. 2019. The role of glia in mechanical (protective) and trophic functions for gut neurons is complemented by neurotransmitter functions, immunological and motor, and when it is affected, clinical symptoms begin that include disorientation, difficulty in memory impairment, emotional problems such as anxiety, irritability and depression.90% of the Serotonin, key in mood, behavior and sleep is synthesized in the large intestine and its balance also depends on intestinal homeostasis, Rutsch A et al. 2020. General objective: Describe the role of the intestinal microbiota and its therapeutic role in neurodegenerative diseases. Methodology: A non-experimental study of a descriptive-correlational type, of bibliographic review, will be carried out. Expected results: Collect information on the relationship between the symbiosis of the gut-brain microbiota system with the presence of neurodegenerative diseases.