Complicaciones Endocrinológicas posterior a Trasplante de Células Progenitoras Hematopoyéticas

Abstract

Introduction: Hematopoietic stem cell engraftment, also known as bone marrow transplantation or hematopoietic progenitor cell transplantation, is a therapeutic procedure that involves the infusion of autologous or allogeneic hematopoietic stem cells into a patient aiming at restoring normal hematopoietic function. Main Findings from the Review: Patients who undergo hematopoietic progenitor cell transplantation tend to experience an extended period of dysfunction, which is caused by the administration of the conditioning regime and the infusion of hematopoietic progenitor cells. Additionally, the type of transplantation is described based on the origin of the progenitor cells, whether autologous, allogeneic, or syngeneic. Understanding post-transplant endocrinological complications is crucial for early decompensation detection, thereby improving outcomes. Conclusions: It is important to note that hematopoietic progenitor cell transplantation is a medical procedure that involves the transfer of hematopoietic stem cells, which are immature cells capable of differentiating into various types of blood cells, including white blood cells, red blood cells, and platelets. This treatment is used to manage various diseases, including leukemia, lymphoma, multiple myeloma, and other conditions associated with the immune system.