Colangiocarcinoma hepático en el embarazo. Caso clínico y revisión de la literatura

Abstract

OBJECTIVE: The cholangiocarcinoma is a malignant hepatic neoplastic disease, is very rare and infrequent in the pregnancy, with an incidence of 10 cases per 10 000 pregnancies. Described with the worst prognosis of tumor pathology due to its late diagnosis, which is mainly due to exacerbation of the symptoms, the initial diagnosis made with the imaging studies such as the ultrasound and the tomography; the treatment is purely surgical. It has a 5-year survival rate of 5 %-10 % and can be confused with other diseases such as the obstructive cholestasis or the HELLP syndrome. CLINICAL CASE: The present case describes a patient with hepatic cholangiocarcinoma during her pregnancy, who came to the clinic due to initially presenting intense pain in the epigastrium and in the right hypochondrium. The diagnosis made through laboratory tests, the tumor markers, the imaging tests (ultrasound, and tomography) and the biopsy. The delivery occurred at week 28 of pregnancy, by cephalovaginal route with preeclampsia and vaginitis; In the postpartum period, the administration of analgesics was restricted due to existing liver damage confirmed by tomography and biopsy. CONCLUSION: In this type of case, the diagnostic and treatment schemes proposed for a non-pregnant woman are due to the infrequency of reports of cholangiocarcinoma in pregnant women.