Complicaciones y resultados clínicos en pacientes con cáncer de ovario recurrente posterior a cirugía CRS Y HIPEC

Abstract

Introduction: Epithelial ovarian cancer (EOC) is characterized by high mortality and recurrence rates. This study focuses on evaluating the efficacy and complication profile associated with the application of Intraperitoneal Hyperthermic Chemotherapy (IPHC) together with Cytoreductive Surgery (CRS) in treating recurrent EOC.

Methodology: Through a non-experimental literature review, relevant studies were selected from PubMed, Scopus, and Web of Science databases. Research studies comprehensively analyzing complications and clinical outcomes in patients with recurrent EOC undergoing IPHC and neoadjuvant chemotherapy were included.

Results: The results indicate significant variability in the postoperative survival of patients, affected by the diversity of protocols used and the particular clinical conditions of each patient. There was a high incidence of severe postoperative complications influenced by intraoperative variables and the preoperative clinical status of the patients.

Conclusions: The combination of IPHC and CRS shows remarkable promise in improving patients' quality of life and prolonging survival in patients with recurrent EOC. However, effective management of postoperative complications is established as a critical element of treatment. Rigorous patient recruitment and clinical optimization before and after surgery are critical to maximize the therapeutic benefits and reduce associated risks.