Elaboración de hilos de sutura a partir de cabuya (agave americana), cilantro (coriandrum sativum) y nitrato de plata

Abstract

The objective of this project was to manufacture suture threads from “cabuya” (American agave), coriander (Coriandrum sativum) as a reducing agent, and silver nitrate (AgNO3) to obtain silver nanoparticles (AgNPs). The suture threads were manufactured from “cabuya” fibers, to which AgNPs were attached as a bacteriostatic and bactericidal mechanism, using an aqueous carrier obtained from coriander extract. Bacterial properties were tested using cultures for S. aureus, and E. coli, showing an inhibition halo of 6 x 4 cm and an average diameter of 1.6 cm. The effectiveness and applicability were tested in two groups of 10 guinea pigs, group AA (“cabuya”) and group 2 NN (polyamide), which were placed in individual boxes for a 30-day adaptation period. After that, two 5 cm lateral surgical incisions were made in the dorsum of the same patient with the help of a 3D printed incision pattern, which was treated with the two sutures. At 8, 15, 21, 21, 45, and 60 days, skin tissue samples were taken to estimate the tissue reaction, degradation, and healing period. The statistical analysis showed no differences between treatments, except for suture degradation, which showed regression of (AA=R^2 0.87 and NN= R^2 0.68). It was concluded that the agave fiber sutures treated with synthesized AgNPs using cilantro keep the same characteristics as the synthetic sutures. Keywords: Cabuya, coriander, guinea pigs, AgNO3, bactericide, bacteriostatic.