Terapia con plasmas de convaleciente añadido al tratamiento de UCI. Una revisión

Abstract

ABSTRACT Introduction: COVID-19 shows itself from asymptomatic to conditions such as insufficiency respiratory, which may need mechanical ventilation that is provided in the intensive care units (ICU). Thus, in cases of multi-organ systematic manifestations such as sepsis and septic shock, the use of plasma from convalescent patients represents a treatment option that nowadays is still in use. Objective: To analyze the scientific production involving the application of plasma therapy from convalescent patients linked to the treatment provided in ICU. Materials and methods: A systematic review of the literature that included quantitative studies, random clinical essays in accordance with the PRISMA criteria. The search of information was conducted through the health terminology (DCS), in databases such as Google scholar, health virtual libraries, and Scopus in both English and Spanish from May to July 2021. Conclusions: The plasma from convalescent patients has been used as therapy for more than a century. The antibodies have an antiviral effect, as well as non-specific anti-inflammatory activity, on its efficacy in SARS-CoV-2 infection, in this case, the COVID-19. Keywords: therapy, convalescent plasma, COVID-19 patient, I.C.U., treatment outcome