Examinando por Autor "Pulla Coronel, Cinthya Elizabeth"
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- ÍtemAcceso AbiertoEtiología, Fisiopatología, Diagnóstico y Tratamiento del Hipotiroidismo en el Embarazo. Revisión Sistemática.(Universidad Católica de Cuenca., 2024) Pulla Coronel, Cinthya Elizabeth; Flores Barrera, Germán Emilio; 0350148953Background: Gestational hypothyroidism is the second cause of endocrinological diseases; subclinical hypothyroidism manifests more frequently, but the clinical one presents greater complications. This research aims to support the best available evidence on hypothyroidism during pregnancy for diagnosis and timely management to reduce maternal and fetal morbidity and mortality. Methodology: This study was a qualitative systematic review based on grounded theory. Databases such as SciELO, PubMed, and Scopus were employed. Inclusion and exclusion criteria and keywords like Hypothyroidism and Thyroid-Stimulating Hormone (TSH) deficiency were considered. The results were recorded and tabulated in Excel and displayed in statistical charts. Results: Etiology of gestational hypothyroidism: Hashimoto's thyroiditis (41%), iodine deficiency (27%), drug-induced (23%); Pathophysiology: Increased iodine clearance and thyroxine-binding globulin; Diagnosis: selective screening (69%), universal (31%). Reference value: TSH greater than 2.5mIU/L (75%), higher than 4mIU/L (25%); Pharmacological treatment for clinical hypothyroidism (100%) and non-pharmacological therapy for subclinical hypothyroidism (86%). Discussion: The etiology coincides with the Ata results; the universal and selective screening diagnosis is controversial. Referential values should be established for each region and each gestational trimester, and treatment should be based on a targeted approach to avoid complications. Others: There is no financial support and no conflicts of interest. Keywords: Hypothyroidism, etiology of hypothyroidism, TSH deficiency.