Examinando por Autor "Rojas Reyes, Greinny Adamaries"
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Ítem Acceso Abierto Efectividad de la vacuna del virus del papiloma humano en la prevención del cáncer cervicouterino. Revisión Sistemática(Universidad Católica de Cuenca., 2024) Rojas Reyes, Greinny Adamaries; Flores Barrera, German Emilio; 1105156242Background: Human Papillomavirus (HPV) is a virus with high oncogenic potential associated with cervical cancer, making it necessary to implement preventive measures aimed at reducing morbidity and mortality. Objective: To determine the effectiveness of the HPV vaccine in preventing cervical cancer. Method: A systematic review based on publications from cohort studies, case-control studies, and literature reviews selected according to inclusion and exclusion criteria from the past five years, retrieved from the databases UpToDate, Web of Science, Scopus, and PubMed. Results: The data were summarized descriptively. Evidence shows that the HPV vaccine is statistically effective when administered to individuals under 14 (OR: 0.39 (0.23-0.64) 95% CI). Multiple studies demonstrate effectiveness with vaccination regimens of one, two, and three doses, including in women with a history of cervical lesions positive for high-risk oncogenic HPV (OR: 0.19 (0.13-0.27) 95% CI). Keywords: Human Papillomavirus, cervical cancer, papillomavirus vaccines
