Examinando por Autor "Molina Bernal , Brittney Lissette"
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Ítem Acceso Abierto Administración de CBD para el manejo de desórdenes de ansiedad en gatos(Universidad Católica de Cuenca., 2025) Molina Bernal , Brittney Lissette; Castillo Hidalgo, Edy Paul; 0107408635The research work focuses on the therapeutic management of anxiety in cats, a topic that generates a growing concern in veterinary medicine due to the high sensitivity of this species to stressors. In this context, the use of cannabidiol (CBD), a non-psychotropic component of cannabis, is explored as a possible therapeutic alternative to reduce symptoms and signs of anxiety in felines. According to a study conducted by (Mentzel et al., 2022), the following prevalence of anxiety disorders has been observed in cats: generalized anxiety disorder (15%), which is characterized by unjustified anxiety; disocialization (23%), which is defined as the absence of social behavior; deterritorialization (14%), which is shown as an alteration of territorial behavior; phobia (1.4%), understood as excessive fear; compulsive disorder (4%), which manifests itself in stereotyped behaviors; dissociative disorder (2%), which includes self-harm; and intermittent explosive aggression (3%), characterized by the presentation of unpredictable aggression. The aim of the present research was to evaluate the efficacy and safety of administering different doses of cannabidiol (CBD) compared to a control group, to determine its effects in cats clinically diagnosed with anxiety disorders. To meet this objective, nine domestic cats (Felis catus) with a clinical diagnosis of anxiety were selected. An experimental design of staggered doses was applied: 0.5 mg/kg and 1.0 mg/kg of CBD, plus a control group that received a placebo (0.9% saline). The observations were carried out for four weeks in rooms equipped to minimize external variables and to be able to objectively record the behavioral parameters that make up the FAS (Fear, anxiety, and stress) scale. Cats receiving 0.5 mg/kg showed a significant reduction in signs and symptoms of anxiety with a low incidence of side effects. In contrast, patients who received a dose of 1.0 mg/kg presented variable responses with a slight increase in side reactions. Compared to the control group, the treated animals showed greater emotional stability, reflecting the potential usefulness of CBD as an alternative treatment for anxiety disorders. Therefore, CBD, and in particular its administration orally at doses of 0.5 mg/kg, is a safe and effective option to reduce the signs of anxiety in felines. However, it is recommended to expand the research with a larger number of patients and longer follow-up periods to confirm these findings and promote their use in clinical practice. Keywords: CBD; cats; anxiety; cannabidiol; FAS scale
