Examinando por Autor "Coello Correa, Santiago Javier"
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- ÍtemAcceso AbiertoDolor agudo postoperatorio con clonixinato de lisina versus sulfato de magnesio(Universidad Católica de Cuenca., 2024) Coello Correa, Santiago Javier; Carrera Reyes, Rosa Eulalia; 0302655211Introduction: Acute postoperative pain occurs after a surgical intervention, which may or may not be planned depending on comorbidities and possible complications during the intraoperative period or a combination of both. These widespread pains are estimated to be present in at least four out of every five patients. They are managed with opioid analgesics. New pharmacological techniques such as magnesium sulfate and lysine clonixinate are being investigated. Objective: To review the management of acute postoperative pain with lysine clonixinate and magnesium sulfate. Methodology: A literature review was conducted using searches on digital platforms such as Elsevier, Springer Link, and PubMed. Keywords like magnesium sulfate, lysine clonixinate, acute postoperative pain, and Boolean operators AND, OR were employed to optimize results. Results: From an original group of 105 scientific articles, 45 were selected as applicable according to predefined objectives. The pharmacological administration of lysine clonixinate and magnesium sulfate in managing acute postoperative pain was effective and safe. The frequent complications presented by magnesium sulfate were bradycardia, hypotension, respiratory paralysis, delayed recovery, and abnormal vision; when lysine clonixinate was administrated gastritis and platelet anti-aggregation occurred. Conclusions: The pharmacological administration of lysine clonixinate and magnesium sulfate in managing acute postoperative pain was effective and safe, providing postoperative analgesia, hemodynamic stability, reduced opioid consumption, and lower rescue analgesia, with a low incidence of complications.