Bioquímica y Farmacia
URI permanente para esta comunidadhttps://dspace.ucacue.edu.ec/handle/ucacue/26
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Ítem Solo Metadatos “Revisión sistemática sobre la prevalencia de bacterias uropatógenas y su resistencia a los antibacterianos en Ecuador (2012 - 2022)”(Universidad Católica de Cuenca., 2023) Molina Arias, Dennise Stefania; Rodríguez Valverde, Jonathan Alexis; Cárdenas Cordero, Janneth Fernanda; 0105488084; 1400974539Introduction: One of the most common bacterial infections worldwide is urinary tract infections (UTIs), affecting about 150 million people annually. The most common pathogens causing urinary tract infections include Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae. Antibacterial agents are used to control UTIs, but due to inappropriate use of therapeutic regimens and self-medication, a global public health problem has emerged: antibacterial resistance. Objective: To compile data on the prevalence of uropathogenic bacteria, profile, and mechanisms of antimicrobial resistance. Methodology: A systematic review was performed between 2012-2022 in different databases such as SciELO, Redalyc, Elsevier, and repositories of different universities in Ecuador. Results: The etiological agent with the highest percentage of prevalence in Ecuador is Escherichia coli at 100%, followed by Staphylococcus spp at 37%, Klebsiella spp at 29%, and Proteus spp at 20.7%. E. coli showed resistance to ampicillin, ampicillin/sulbactam, and ampicillin/amoxicillin in 100%, while Klebsiella spp is 100% resistant to ampicillin/sulbactam, cephalothin, cefazolin, cefuroxime, ceftriaxone, gentamicin, ciprofloxacin, and nitrofurantoin. On the other hand, Proteus spp showed resistance to ampicillin at 85.71%, nitrofurantoin at 77.8%, and nalidixic acid at 75%. Conclusion: Based on the systematic review of 47 studies, the most prevalent etiological agents causing UTI and their antimicrobial resistance profiles were determined.
