Examinando por Autor "Tinizaray Carrión , Angela Melisa"
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- ÍtemAcceso AbiertoSíndrome antifosfolipídico(Universidad Católica de Cuenca., 2024) González Tene, Lourdes Aurora; Tinizaray Carrión , Angela Melisa; Siguenza Pacheco , Marco Antonio; 1900832948; 1950001527Antiphospholipid syndrome (APS), also known as Hughes syndrome, was first described in 1983. This disorder is characterized by mistakenly attacking normal blood proteins, causing hypercoagulability, and contributing to the formation of blood clots in veins, arteries, and organs. There are two types of APS: Primary APS (PAPS) and Secondary APS (SAPS), which is understood as secondary when it is accompanied by other diseases that affect the immune system, as in the case of systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sjögren's syndrome; it is referred as primary when it occurs without any visible cause. In addition, in specific cases, it is called catastrophic APS, which generates a multiorgan failure and can cause the death of those who suffer from it. Its worldwide prevalence is estimated at 1 to 5%, which represents 40 to 50 cases per 100,000 individuals of the world population. This syndrome affects more females than males, and in pregnant women, there is a higher risk of miscarriages and stillbirths. The most commonly used treatment for this syndrome is anticoagulants; in the case of pregnant women, heparin and low-dose aspirin have been used. The factors for diagnosis include age and gender, and, in the case of a woman, to verify that the patient is not pregnant.