Sede Azogues - Medicina
URI permanente para esta comunidadhttps://dspace.ucacue.edu.ec/handle/ucacue/88
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Examinando Sede Azogues - Medicina por Autor "Andrade Tenezaca, Karla Tatiana"
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Ítem Acceso Abierto Uso del ácido trenexámico en hemorragia digestiva alta(Universidad Católica de Cuenca., 2023) Andrade Tenezaca, Karla Tatiana; Crespo Vintimilla, Edgar Adriano; 0302882337Abstract: Gastroenterological diseases are frequently attended to in the emergency department, with upper gastrointestinal bleeding having a higher incidence, making it a worldwide issue that must be detected early and effectively treated. Tranexamic acid (ATX) is an antifibrinolytic agent that stops and controls bleeding, with the advantage of achieving good hemostasis and maintaining tissue perfusion, thus seeking to be incorporated into treating upper gastrointestinal bleeding. Objective: To analyze the effectiveness of the administration of tranexamic acid for the emergency treatment of upper gastrointestinal bleeding. Methodology: Qualitative research with a non-experimental, descriptive, and analytical literature review design. Scientific articles published since 2019 in Spanish, Portuguese, and English were used from scientific search engines such as Elsevier, Scopus, PubMed, Google Scholar, SciELO, and UpToDate. Results: A total of 33 articles (70.21%) were included, corresponding to the following figures in the database: 3 (6.38%) Elsevier, 15 (31.91%) PubMed, 4 (8.51%) UpToDate, 5 (10.63%) Google Scholar, 3 (6.38%) SciELO, 1 (2.12%) Polo del Conocimiento, and 2 (4.25%) Medigraphic. Conclusions: After the analysis, ATX is not recommended as a routine treatment for upper gastrointestinal bleeding due to its few benefits and higher propensity to thromboembolic events. The decision to use TAX in a patient with gastrointestinal bleeding should be individualized and based on a case-specific risk-benefit assessment.
