Probiotics and gut microbiota in obesity: myths and realities of a new health revolution

dc.contributor.advisorBermúdez Pirela, Valmore
dc.contributor.authorLeón Aguilera, Xavier Eugenio
dc.coverageCuenca-Ecuadores_ES
dc.date.accessioned2022-10-29T20:52:23Z
dc.date.available2022-10-29T20:52:23Z
dc.date.issued2022
dc.descriptionObesity and its comorbidities are humans’ most prevalent cardio-metabolic diseases worldwide. Recent evidence has shown that chronic low-grade inflammation is a common feature in all highly prevalent chronic degenerative diseases. In this sense, the gut microbiota is a complete ecosystem involved in different processes like vitamin synthesis, metabolism regulation, and both appetite and immune system control. Thus, dysbiosis has been recognised as one of the many factors associated with obesity due to a predominance of Firmicutes, a decrease in Bifidobacterium in the gut, and a consequent short-chain fatty acids (SCFA) synthesis reduction leading to a reduction in incretins action and intestinal permeability increase. In this context, bacteria, bacterial endotoxins, and toxic bacterial by-products are translocated to the bloodstream, leading to systemic inflammation. This review focuses on gut microbiota composition and its role in obesity, as well as probiotics and prebiotics benefits in obesityes_ES
dc.description.uriTrabajo de investigaciónes_ES
dc.formatapplication/pdfes_ES
dc.identifier.citationLeón Aguilera, X.E.; Manzano, A.; Pirela, D.; Bermúdez, V. Probiotics and Gut Microbiota in Obesity: Myths and Realities of a New Health Revolution. J. Pers. Med. 2022, 12, 1282es_ES
dc.identifier.doihttps://doi.org/10.3390/jpm12081282es_ES
dc.identifier.journal Journal of Personalized Medicinees_ES
dc.identifier.other19B-2022-TMC4
dc.identifier.urihttps://dspace.ucacue.edu.ec/handle/ucacue/12688
dc.language.isoenges_ES
dc.publisherUniversidad Católica de Cuencaes_ES
dc.rightsinfo:eu-repo/semantics/embargoedAccesses_ES
dc.sourceUNIVERSIDAD CATÓLICA DE CUENCAes_ES
dc.subjectobesity; es_ES
dc.subjectgut microbiota;es_ES
dc.subject short chain fatty acids; es_ES
dc.subjectprobiotics; es_ES
dc.subjectprebioticses_ES
dc.titleProbiotics and gut microbiota in obesity: myths and realities of a new health revolutiones_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
thesis.degree.levelMaestríaes_ES
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